Neonatal Early-Onset Sepsis Risk (Kaiser EOS Framework) — free guideline decision tool
The Kaiser Permanente early-onset sepsis (EOS) framework combines perinatal risk factors with the infant's clinical examination to stratify management in newborns ≥ 34–35 weeks.
Open guideline tool →Guideline-based
Implements the decision logic from published clinical guidelines.
Runs in your browser
No installation. Enter the patient's values and get a guideline recommendation instantly.
Data stays local
Nothing is uploaded. Results are for licensed clinicians only.
Common questions
What does Neonatal Early-Onset Sepsis Risk (Kaiser EOS Framework) do?
Use in well-appearing-to-ill newborns ≥ 34–35 weeks to decide between routine care, enhanced observation, and blood culture plus empiric antibiotics.
How is the result calculated?
Birth risk derives from GA, maximum maternal intrapartum temperature, ROM duration, GBS and intrapartum antibiotics; combined with clinical grade — risk < 1/1000 routine, 1–3 enhanced observation ± culture, > 3 culture + antibiotics; clinical illness → culture + antibiotics regardless of risk.
Is this a substitute for clinical judgement?
No. All results are decision-support only, for licensed clinicians. They must be individualized to the whole patient and the latest guideline version.
Run Neonatal Early-Onset Sepsis Risk (Kaiser EOS Framework) now
The Kaiser Permanente early-onset sepsis (EOS) framework combines perinatal risk factors with the infant's clinical examination to stratify management in newborns ≥ 34–35 weeks.
Open guideline tool →For licensed clinicians. Not a substitute for clinical judgement.