Clinical Pulmonary Infection Score (CPIS) — free guideline decision tool
Support diagnosis of ventilator-associated pneumonia with the CPIS.
Open guideline tool →Guideline-based
Implements the decision logic from published clinical guidelines.
Runs in your browser
No installation. Enter the patient's values and get a guideline recommendation instantly.
Data stays local
Nothing is uploaded. Results are for licensed clinicians only.
Worked calculation
The values below come from this tool's own example placeholders and are computed server-side with the formula shown on this page, so the arithmetic can be checked quickly. It demonstrates how to substitute values only — it is not clinical advice and not a real case.
| Temperature | 36.5–38.4 °C (0) |
|---|---|
| WBC (×10⁹/L) | 4–11 (0) |
| Tracheal secretions | None (0) |
| PaO₂/FiO₂ | > 240 or ARDS (0) |
| Chest radiograph | No infiltrate (0) |
| Tracheal aspirate culture | None/light growth (0) |
→CPIS0/12
- Interpretation：≤ 6 — pneumonia less likely
- Note：CPIS has only moderate accuracy for VAP; use alongside clinical judgement and microbiology, not as a sole criterion.
| Temperature | ≥ 39 or ≤ 36 (2) |
|---|---|
| WBC (×10⁹/L) | Plus bands ≥ 50% (2) |
| Tracheal secretions | Purulent (2) |
| PaO₂/FiO₂ | ≤ 240, no ARDS (2) |
| Chest radiograph | Localised (2) |
| Tracheal aspirate culture | Plus same on Gram stain (2) |
→CPIS12/12
- Interpretation：> 6 — pneumonia likely
- Note：CPIS has only moderate accuracy for VAP; use alongside clinical judgement and microbiology, not as a sole criterion.
Common questions
What is Clinical Pulmonary Infection Score (CPIS)?
Support diagnosis of ventilator-associated pneumonia with the CPIS.
How is Clinical Pulmonary Infection Score (CPIS) calculated? What is the core formula?
Temperature, WBC, secretions, PaO₂/FiO₂, chest radiograph and culture — each 0–2. > 6 suggests pneumonia.
When is Clinical Pulmonary Infection Score (CPIS) used?
Adjunct to clinical judgement in suspected VAP.
What are the key clinical points for Clinical Pulmonary Infection Score (CPIS)?
Only moderate accuracy for VAP. Not a sole basis for antibiotic decisions. Combine with microbiology and clinical course.
What are the limits and cautions when using Clinical Pulmonary Infection Score (CPIS)?
For licensed clinicians and clinical researchers. Interpret results with history, investigations and local protocols; not a diagnosis or prescription, and not a substitute for multidisciplinary decision-making or local guidelines.
How is Clinical Pulmonary Infection Score (CPIS) calculated in practice? Can you show a worked example?
Inputs: Temperature 36.5–38.4 °C (0), WBC (×10⁹/L) 4–11 (0), Tracheal secretions None (0), PaO₂/FiO₂ > 240 or ARDS (0), Chest radiograph No infiltrate (0), Tracheal aspirate culture None/light growth (0) → Result: CPIS 0 /12（Interpretation: ≤ 6 — pneumonia less likely, Note: CPIS has only moderate accuracy for VAP; use alongside clinical judgement and microbiology, not as a sole criterion.） Inputs: Temperature ≥ 39 or ≤ 36 (2), WBC (×10⁹/L) Plus bands ≥ 50% (2), Tracheal secretions Purulent (2), PaO₂/FiO₂ ≤ 240, no ARDS (2), Chest radiograph Localised (2), Tracheal aspirate culture Plus same on Gram stain (2) → Result: CPIS 12 /12（Interpretation: > 6 — pneumonia likely, Note: CPIS has only moderate accuracy for VAP; use alongside clinical judgement and microbiology, not as a sole criterion.）
Run Clinical Pulmonary Infection Score (CPIS) now
Support diagnosis of ventilator-associated pneumonia with the CPIS.
Open guideline tool →For licensed clinicians. Not a substitute for clinical judgement.
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