CKD Anemia of Renal Disease Management — free guideline decision tool
This tool manages anemia of CKD by hemoglobin and iron status (ferritin/TSAT) and dialysis modality, directing iron, ESA/HIF-PHI, and the Hb target.
Open guideline tool →Guideline-based
Implements the decision logic from published clinical guidelines.
Runs in your browser
No installation. Enter the patient's values and get a guideline recommendation instantly.
Data stays local
Nothing is uploaded. Results are for licensed clinicians only.
Worked calculation
The values below come from this tool's own example placeholders and are computed server-side with the formula shown on this page, so the arithmetic can be checked quickly. It demonstrates how to substitute values only — it is not clinical advice and not a real case.
| Hemoglobin Hb | 95 g/L |
|---|---|
| Serum ferritin SF | 120 ng/mL |
| Transferrin saturation TSAT | 18 % |
| Dialysis modality | Non-dialysis / peritoneal dialysis |
→DispositionStart anemia correction
- Iron status & supplementation：Iron deficiency present (non-dialysis/PD SF < 100 and/or TSAT < 20%): give iron first (oral or IV for non-dialysis, usually IV for dialysis; avoid IV iron in active infection/bacteremia)
- ESA/HIF-PHI：Start an erythropoiesis-stimulating agent (ESA, first-line) or HIF-PHI (roxadustat): correct iron deficiency and reversible factors (inflammation, bleeding, nutrition, etc.) and exclude other anemia causes first
- Target：Hb ≥ 110 and ≤ 130 g/L, individualized (age, dialysis modality, comorbidities); avoid a Hb rise > 10 g/L within 4 weeks
Common questions
What is CKD Anemia of Renal Disease Management?
This tool manages anemia of CKD by hemoglobin and iron status (ferritin/TSAT) and dialysis modality, directing iron, ESA/HIF-PHI, and the Hb target.
How is CKD Anemia of Renal Disease Management calculated? What is the core formula?
Iron deficiency: non-dialysis/PD SF < 100 or TSAT < 20%, hemodialysis SF < 200 or TSAT < 20%; SF > 500 no routine IV iron. Hb < 100 → start ESA/HIF-PHI; target Hb ≥ 110 and ≤ 130; avoid > 10 g/L rise in 4 weeks.
When is CKD Anemia of Renal Disease Management used?
Use to decide on iron supplementation, ESA or HIF-PHI initiation, and to keep hemoglobin within the target band while avoiding overshoot.
What are the key clinical points for CKD Anemia of Renal Disease Management?
Iron deficiency and reversible factors are corrected before starting an ESA, and an excessively rapid hemoglobin rise is avoided. (original synthesis · not guideline verbatim) Hemodialysis uses a higher ferritin threshold (SF < 200) than non-dialysis/PD (SF < 100). Hb > 130 prompts dose reduction because excessive levels raise thrombosis and death risk.
What are the limits and cautions when using CKD Anemia of Renal Disease Management?
For licensed clinicians and clinical researchers. Interpret results with history, investigations and local protocols; not a diagnosis or prescription, and not a substitute for multidisciplinary decision-making or local guidelines.
How is CKD Anemia of Renal Disease Management calculated in practice? Can you show a worked example?
Inputs: Hemoglobin Hb 95 g/L, Serum ferritin SF 120 ng/mL, Transferrin saturation TSAT 18 %, Dialysis modality Non-dialysis / peritoneal dialysis → Result: Disposition Start anemia correction（Iron status & supplementation: Iron deficiency present (non-dialysis/PD SF < 100 and/or TSAT < 20%): give iron first (oral or IV for non-dialysis, usually IV for dialysis; avoid IV iron in active infection/bacteremia), ESA/HIF-PHI: Start an erythropoiesis-stimulating agent (ESA, first-line) or HIF-PHI (roxadustat): correct iron deficiency and reversible factors (inflammation, bleeding, nutrition, etc.) and exclude other anemia causes first, Target: Hb ≥ 110 and ≤ 130 g/L, individualized (age, dialysis modality, comorbidities); avoid a Hb rise > 10 g/L within 4 weeks）
Run CKD Anemia of Renal Disease Management now
This tool manages anemia of CKD by hemoglobin and iron status (ferritin/TSAT) and dialysis modality, directing iron, ESA/HIF-PHI, and the Hb target.
Open guideline tool →For licensed clinicians. Not a substitute for clinical judgement.
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