Guideline decision tool · Infectious disease
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Clostridioides difficile Infection (CDI) Treatment — free guideline decision tool

This tool gives the Clostridioides difficile infection regimen by episode and severity, covering initial, recurrent, and fulminant disease.

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Computed locally — no data uploaded. For licensed clinicians.
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Guideline-based

Implements the decision logic from published clinical guidelines.

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Runs in your browser

No installation. Enter the patient's values and get a guideline recommendation instantly.

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Data stays local

Nothing is uploaded. Results are for licensed clinicians only.

Common questions

What does Clostridioides difficile Infection (CDI) Treatment do?

Use to choose fidaxomicin or vancomycin for initial/recurrent CDI, taper-pulse or FMT for multiple recurrences, and high-dose vancomycin + IV metronidazole for fulminant disease.

How is the result calculated?

Initial (non-severe/severe) → fidaxomicin or oral vancomycin × 10 days. First recurrence → fidaxomicin or vancomycin taper-pulse. Multiple recurrences → taper-pulse/rifaximin/FMT. Fulminant → high-dose vancomycin + IV metronidazole + surgery.

Is this a substitute for clinical judgement?

No. All results are decision-support only, for licensed clinicians. They must be individualized to the whole patient and the latest guideline version.

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Run Clostridioides difficile Infection (CDI) Treatment now

This tool gives the Clostridioides difficile infection regimen by episode and severity, covering initial, recurrent, and fulminant disease.

Open guideline tool →

For licensed clinicians. Not a substitute for clinical judgement.

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Related guideline tools

For use by licensed clinicians and clinical researchers. Computed locally in your browser — no data is uploaded. Not a substitute for clinical judgement.