Anaphylaxis / Anaphylactic Shock Management — free guideline decision tool
Compute the weight-based IM epinephrine dose and give positioning, fluids and follow-on steps by hypotension/refractory/beta-blocker status. Instant, browser-side.
Open guideline tool →Guideline-based
Implements the decision logic from published clinical guidelines.
Runs in your browser
No installation. Enter the patient's values and get a guideline recommendation instantly.
Data stays local
Nothing is uploaded. Results are for licensed clinicians only.
Worked calculation
The values below come from this tool's own example placeholders and are computed server-side with the formula shown on this page, so the arithmetic can be checked quickly. It demonstrates how to substitute values only — it is not clinical advice and not a real case.
| Weight (to estimate epinephrine dose) | 60 kg |
|---|---|
| Hypotension/shock | Yes |
| Persists after two IM doses | Yes |
| On a beta-blocker | Yes |
→Primary actionImmediate IM epinephrine 0.5 mg
- First-line (immediate)：IM epinephrine 0.5 mg (1 mg/mL) into the mid-outer thigh (vastus lateralis), repeatable in 5–15 min; do not delay for antihistamines/steroids
- Positioning：Supine with legs elevated (semi-recumbent if dyspneic); avoid sudden sitting up/standing
- Fluids：High-flow oxygen + rapid IV crystalloid 1–2 L to correct hypotension
Common questions
What is Anaphylaxis / Anaphylactic Shock Management?
Compute the weight-based IM epinephrine dose and give positioning, fluids and follow-on steps by hypotension/refractory/beta-blocker status. Instant, browser-side.
How is Anaphylaxis / Anaphylactic Shock Management calculated? What is the core formula?
IM epinephrine 0.01 mg/kg (adult max 0.5 mg, child max 0.3 mg) into the mid-outer thigh, repeatable every 5–15 min. Hypotension → supine with legs up + oxygen + rapid crystalloid 1–2 L. Persisting after two IM doses → IV epinephrine infusion (monitored). On a beta-blocker and refractory → glucagon.
When is Anaphylaxis / Anaphylactic Shock Management used?
Emergency management of anaphylaxis and anaphylactic shock.
What are the key clinical points for Anaphylaxis / Anaphylactic Shock Management?
IM epinephrine is the first-line and only life-saving drug — never delayed for antihistamines or steroids. Antihistamines (H1 ± H2) and corticosteroids are adjuncts only and do not replace epinephrine. Watch for biphasic reactions requiring observation; discharge with an epinephrine auto-injector and trigger-avoidance education. Glucagon is the option when a beta-blocked patient responds poorly to epinephrine.
What are the limits and cautions when using Anaphylaxis / Anaphylactic Shock Management?
For licensed clinicians and clinical researchers. Interpret results with history, investigations and local protocols; not a diagnosis or prescription, and not a substitute for multidisciplinary decision-making or local guidelines.
How is Anaphylaxis / Anaphylactic Shock Management calculated in practice? Can you show a worked example?
Inputs: Weight (to estimate epinephrine dose) 60 kg, Hypotension/shock Yes, Persists after two IM doses Yes, On a beta-blocker Yes → Result: Primary action Immediate IM epinephrine 0.5 mg（First-line (immediate): IM epinephrine 0.5 mg (1 mg/mL) into the mid-outer thigh (vastus lateralis), repeatable in 5–15 min; do not delay for antihistamines/steroids, Positioning: Supine with legs elevated (semi-recumbent if dyspneic); avoid sudden sitting up/standing, Fluids: High-flow oxygen + rapid IV crystalloid 1–2 L to correct hypotension）
Run Anaphylaxis / Anaphylactic Shock Management now
Compute the weight-based IM epinephrine dose and give positioning, fluids and follow-on steps by hypotension/refractory/beta-blocker status. Instant, browser-side.
Open guideline tool →For licensed clinicians. Not a substitute for clinical judgement.
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