Case challenge · Imaging / Fetal medicine / Prenatal diagnosis · teaching

Fetal Malformation of Cortical Development (MCD) MRI · case challenge

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← View the full flowchartBased on Barkovich classification

Case #1Imaging / Fetal medicine / Prenatal diagnosis

📋 Case data

Sulcation/cortical pattern (against gestation)Gray-matter-lined cleft (ependyma to pia)

Data is taken from this pathway's reviewed node text. Work through the pathway step by step.

Step 1 / 1 · Sulcation/cortical pattern (against gestation)

Sulcation / cortical pattern (against gestation)?

💡 MCD by the Barkovich classification (abnormal proliferation/migration/post-migrational organization). Key fetal MRI feature = sulcation timing (against gestation). Hard to assess <20–24 weeks, recheck at 24–34 weeks (mild sulcation delay may normalize), confirm on postnatal MRI. With abnormal sulcation, also check CC/posterior fossa/calcification/head circumference.

For teaching. Decisions and their basis are taken from this site's reviewed care pathways; for licensed clinicians/trainees, this does not replace clinical judgment or local protocols.