Case challenge · Imaging / Fetal medicine / Prenatal diagnosis · teaching

Fetal Agenesis of the Corpus Callosum MRI · case challenge

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Case #1Imaging / Fetal medicine / Prenatal diagnosis

📋 Case data

Corpus callosum MRI assessmentPartial agenesis/hypoplasia (usually missing splenium/rostrum)

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Step 1 / 1 · Corpus callosum MRI assessment

Corpus callosum MRI assessment (midsagittal direct visualization)?

💡 The CC develops front-to-back at 10–18/20 weeks (genu first, splenium/rostrum last). MRI is superior to ultrasound (midsagittal directly shows the CC; ultrasound relies on indirect signs like absent cavum septi pellucidi). Suspect a CC anomaly when there is ventriculomegaly.

For teaching. Decisions and their basis are taken from this site's reviewed care pathways; for licensed clinicians/trainees, this does not replace clinical judgment or local protocols.